Project Title: “Jammer” systems for Staphylococcus aureus: Molecularly suppressed polymers that silence bacterial signals
Project Leader: Assoc. Prof. Dr. Ömür Acet
School of Health Services
Department of Pharmacy Services
Research Institution: Hacettepe University
Project Duration: 18 Months
The ‘jammer’ systems developed for Staphylococcus aureus represent a novel approach that aims to disrupt bacterial communication rather than eliminate the bacteria. These bacteria communicate via chemical signals to cause disease and decide when to produce toxins or form biofilms. Molecularly imprinted polymers are smart materials that act like a sponge, capturing and binding these signalling molecules through a special 3D recognition mechanism. With these smart materials, bacteria cannot initiate harmful behaviours. As a result, even if the bacteria survive, they cause less harm or no harm at all, and their ability to cause infection is reduced. This method offers a smarter and more targeted solution than antibiotics, making it more difficult for bacteria to develop resistance.